Skip to main content

The fan casting platform. Cast your favorite talent in movies, TV shows, and more.

Powered by

Browse

Stories
Talent
Tags
Community

Company

About
Fan Cast News
Contact
Privacy Policy
Terms of Use

Community

Forums
Add a Story
Help & FAQ

© 2026 myCast.io. All rights reserved.

/

Mister Sinister Fan Casting | myCast.io

Fan Casting
Talent
Mister Sinister (Dr. Nathaniel Essex)

Mister Sinister (Dr. Nathaniel Essex)

Mister Sinister (Dr. Nathaniel Essex)

Age: 39

born October 7, 1986

male155 suggestions0 votes

About Mister Sinister (Dr. Nathaniel Essex) Photos

Dr. Nathaniel Essex, also known as Mister Sinister, is a fictional character and supervillain appearing in American comic books published by Marvel. He is a Victorian England scientist who was inspired by the work of his contemporary Charles Darwin and becomes obsessed with engineering humanity into a perfect race of superhumans. As he learns about mutants (superhuman beings born with the X-gene), Essex encounters the mutant villain Apocalypse. The two become allies and Apocalypse uses alien Celestial technology to transform the British scientist into Mr. Sinister, an ageless man with superpowers. Later on, Sinister increases his power through self-experimentation. In the modern-day, Sinister develops a great, but obsessive interest and protective attitude towards the mutant heroes Cyclops and Jean Grey, believing their DNA can create the ultimate mutant, making him a recurring foe of the X-Men.

Top Casting Suggestions

Mister Sinister (Dr. Nathaniel Essex) has been suggested to play 155 roles. Click below to see other actors suggested for each role, and vote for who you think would play the role best.

Top Voted Newest First Oldest First

Top Casting Suggestions

Mister Sinister (Dr. Nathaniel Essex) has been suggested to play 155 roles. Click below to see other actors suggested for each role, and vote for who you think would play the role best.

Top Voted Newest First Oldest First

Mister Sinister (Dr. Nathaniel Essex)

as

Future Team Up With The Villains Of X-Men vs Street Fighter 2

in

Future Alliances I Want To See It In Marvel vs Capcom.

Future Team Up With The Villains Of X-Men vs Street Fighter 2

Future Team Up With The Villains Of X-Men vs Street Fighter 2

Mister Sinister (Dr. Nathaniel Essex)

as

Future Sub-Bosses Of Future Marvel vs Capcom and Vs Street Fighter.

in

Future Final Giants Boss I Want To See In Future Marvel vs Capcom Games.

Future Sub-Bosses Of Future Marvel vs Capcom and Vs Street Fighter.

Future Sub-Bosses Of Future Marvel vs Capcom and Vs Street Fighter.

Mister Sinister (Dr. Nathaniel Essex)

as

Marvel

in

Vote for your fave Fictionals Characters

Marvel

Marvel

Mister Sinister (Dr. Nathaniel Essex)

as

Main Villains I Want To See It In The Mutant Saga

in

Main Villains I Want To See It In Three Arcs In The Mutant Saga,

Main Villains I Want To See It In The Mutant Saga

Main Villains I Want To See It In The Mutant Saga

Mister Sinister (Dr. Nathaniel Essex)

as

Who Should Sing Bye Bye

in

Toonking1985's Voting Page

Who Should Sing Bye Bye

Who Should Sing Bye Bye

Mister Sinister (Dr. Nathaniel Essex)

as

Future Villains I Want To See It In Avengers ReAssembled

in

Future Héroes And Future Villains I Want To See It In Avengers ReAssembled

Future Villains I Want To See It In Avengers ReAssembled

Future Villains I Want To See It In Avengers ReAssembled

Mister Sinister (Dr. Nathaniel Essex)

as

Torin Thatcher

in

Deceased Actors’ Casting You Would’ve Loved to See

Torin Thatcher

Torin Thatcher

Mister Sinister (Dr. Nathaniel Essex)

as

X-Men

in

Marvel Rivals

X-Men

X-Men

Mister Sinister (Dr. Nathaniel Essex)

as

Alan Rickman

in

Which characters should actors have played in the 80’s?

Alan Rickman

Alan Rickman

Mister Sinister (Dr. Nathaniel Essex)

as

The man Cable warned them about

in

X-Men: Age Of Apocalypse

The man Cable warned them about

The man Cable warned them about

Mister Sinister (Dr. Nathaniel Essex)

as

Potential Villains

in

Marvel Rivals

Potential Villains

Potential Villains

Mister Sinister (Dr. Nathaniel Essex)

as

What if Sean Connery was in Marvel's The Avengers?

in

myFiction

What if Sean Connery was in Marvel's The Avengers?

What if Sean Connery was in Marvel's The Avengers?

Mister Sinister (Dr. Nathaniel Essex)

as

Kevin Michael Richardson

in

Comic Book Voice Actors that Should Reprise Roles

Kevin Michael Richardson

Kevin Michael Richardson

Mister Sinister (Dr. Nathaniel Essex)

as

1st X-men villain introduced into the MCU

in

The X-Men Phase

1st X-men villain introduced into the MCU

1st X-men villain introduced into the MCU

Mister Sinister (Dr. Nathaniel Essex)

as

Marvel

in

Marvel and DC characters that could be played by Keanu Reeves

Marvel

Marvel

Mister Sinister (Dr. Nathaniel Essex)

as

First Villain

in

Wich Characters Should Be In The X-men team in the mcu

First Villain

First Villain

Mister Sinister (Dr. Nathaniel Essex)

as

The Marauders

in

Wich Characters Should Be In The X-men team in the mcu

The Marauders

The Marauders

Mister Sinister (Dr. Nathaniel Essex)

as

Best Villain

in

The Best & Worst Of Marvel

Best Villain

Best Villain

Mister Sinister (Dr. Nathaniel Essex)

as

Enemies of Chiro

in

Friends and Enemies of Fictional Characters (My Version)

Enemies of Chiro

Enemies of Chiro

Mister Sinister (Dr. Nathaniel Essex)

as

1987

in

Character Face Claims Sorted By Year

1987

1987

Mister Sinister (Dr. Nathaniel Essex)

as

Henry Cavill

in

Which Characters Would You Like To See Actors Play In Live Action

Henry Cavill

Henry Cavill

Mister Sinister (Dr. Nathaniel Essex)

as

Kevin Michael Richardson

in

Nathanewing’s favorite characters portrayed by people

Kevin Michael Richardson

Kevin Michael Richardson

Mister Sinister (Dr. Nathaniel Essex)

as

Fred Tatasciore

in

Comic Book Voice Actors that Should Reprise Roles

Fred Tatasciore

Fred Tatasciore

Mister Sinister (Dr. Nathaniel Essex)

as

Red Eyes, Take Warning

in

Characters Sorted by TV Tropes Categories

Red Eyes, Take Warning

Red Eyes, Take Warning

Showing 97–120 of 155 suggestions

Previous 1 2 3 4 5 6 7 Next