Suggestions by @timjeromy12

Eminem

as Spider-Man Rapper (Slim Shady) in Main Classic Marvel Extended Cinematic Universe (MCMECU)

Ryan Reynolds

as Hannibal King in Marvel Knights (2013)

Jessica Biel

as Abigail Whistler in Marvel Knights (2013)

Benicio del Toro

as Morbius (Dr Michael Morbius) in Marvel Knights (2013)

Angela Bassett

as Misty Knight in Marvel Knights (2013)

Eliza Dushku

as Black Cat (Felicia Hardy) in Marvel Knights (2013)

David Hasselhoff

as Nick Fury (Nicholas Joseph Fury) in Marvel Knights (2013)

Eric Bana

as Hulk (Bruce Banner) in Marvel Knights (2013)

Michael Clarke Duncan

as Kingpin (Wilson Fisk) in Marvel Knights (2013)

Guy Pearce

as Moon Knight (Marc Spector) in Marvel Knights (2013)

Hugh Jackman

as Wolverine (James Howlett) in Marvel Knights (2013)

Michael Jai White

as Luke Cage (Carl Lucas) in Marvel Knights (2013)

Djimon Hounsou

as Black Panther (T'Challa) in Marvel Knights (2013)

Tobey Maguire

as Spider-Man (Peter Parker) in Marvel Knights (2013)

Thomas Jane

as Punisher (Frank Castle) in Marvel Knights (2013)

Ben Affleck

as Daredevil (Matt Murdock) in Marvel Knights (2013)

Nicolas Cage

as Ghost Rider (Johnny Blaze) in Marvel Knights (2013)

Wesley Snipes

as Blade (Eric Brooks) in Marvel Knights (2013)

Benicio del Toro

as Morbius (Dr Michael Morbius) in My Sam Raimi's Spider-Man Fancasting

Daniel Gillies

as Man-Wolf (John Jameson) in My Sam Raimi's Spider-Man Fancasting