Suggestions by @themegacaster

Kathy Bates

as Sister Thornly in The Time Squad

Taika Waititi

as Director in The Time Squad

John Candy

as Harvey in The Fantastic Four: First Steps [1985]

Raúl Juliá

as Reed Richards in The Fantastic Four: First Steps [1985]

Maria Zhang

as Princess Peach in Asian Princess Peach

Ulysses Klaw

as Amputee in Canonically Disabled Characters

Michael Sinterniklaas

as Scott Pilgrim (animation) in Casting a random character every saturday #25: Scott Pilgrim

Destin Daniel Cretton

as Director in Teenage Mutant Ninja Turtles: Mutants Unleashed

Time Squad

as Next Project: in Teenage Mutant Ninja Turtles: Mutants Unleashed

Dante Basco

as Panda Kahn in Teenage Mutant Ninja Turtles: Mutants Unleashed

Paul Nakauchi

as Master Splinter in Teenage Mutant Ninja Turtles: Mutants Unleashed

Owen Wilson

as Dr. Harold Lilja in Teenage Mutant Ninja Turtles: Mutants Unleashed

Bo Bragason

as April O’Neil in Teenage Mutant Ninja Turtles: Mutants Unleashed

Sebastian Maniscalco

as Pizzaface in Teenage Mutant Ninja Turtles: Mutants Unleashed

Pat Fraley

as Krang in Teenage Mutant Ninja Turtles: Mutants Unleashed

Shamon Brown Jr.

as Michelangelo in Teenage Mutant Ninja Turtles: Mutants Unleashed

Eminem

as Ray Fillet in Teenage Mutant Ninja Turtles: Mutants Unleashed

Ebon Moss-Bachrach

as Leatherhead in Teenage Mutant Ninja Turtles: Mutants Unleashed

Sean Astin

as Raphael in Teenage Mutant Ninja Turtles: Mutants Unleashed

Noel Fisher

as Mondo Gecko in Teenage Mutant Ninja Turtles: Mutants Unleashed