Suggestions by @ theanimaltrail

Benedict Cumberbatch

as Alfred Pennyworth in Batman (2039)

Pedro Pascal

as Ironman in New MCU(if included Spiderman and Venom)

Jason Isaacs

as Magneto in New MCU(if included Spiderman and Venom)

Jodie Comer

as Mystique in New MCU(if included Spiderman and Venom)

+1-3Score: -2

Glen Powell

as Nova in New MCU(if included Spiderman and Venom)

DeWanda Wise

as Storm in New MCU(if included Spiderman and Venom)

William Jackson Harper

as Reed Richards in New MCU(if included Spiderman and Venom)

Jason Segel

as The Thing in New MCU(if included Spiderman and Venom)

Alden Ehrenreich

as Cyclops in New MCU(if included Spiderman and Venom)

Bryce Dallas Howard

as Sue Storm in New MCU(if included Spiderman and Venom)

Emma Watson

as Jean Grey in New MCU(if included Spiderman and Venom)

Noah Schnapp

as Spiderman in New MCU(if included Spiderman and Venom)

+2-3Score: -1

Joe Keery

as Human Torch in New MCU(if included Spiderman and Venom)

+3-1Score: +2

Jared Keeso

as Wolverine in New MCU(if included Spiderman and Venom)

+1-2Score: -1

Joe Keery

as Batman in Batman (2039)

+1-2Score: -1

James Earl Jones

as Eleven in Recasting Famous Roles

+2-6Score: -4

Elya Baskin

as Best Memes in Best & Worst Comic Book Castings

+5-1Score: +4

Joel Kinnaman

as Sabertooth in X-Men

Hafþór Júlíus Björnsson

as Juggernaut in X-Men