Suggestions by @teokolar

Vicent D'Onofrio

as Wilson Fisk in Casting a Spider-Man animated universe!

Jake Gyllenhaal

as Quentin Beck in Casting a Spider-Man animated universe!

Dwayne Johnson

as Aleksei Sytsevich in Casting a Spider-Man animated universe!

David Thewlis

as The Lizard in Casting a Spider-Man animated universe!

David Thewlis

as Dr. Curtis Connors in Casting a Spider-Man animated universe!

Tom Hardy

as Eddie Brock in Casting a Spider-Man animated universe!

Michael Fassbender

as Flint Marko in Casting a Spider-Man animated universe!

Colman Domingo

as Green Goblin in Casting a Spider-Man animated universe!

Colin Firth

as Dr. Otto Octavius in Casting a Spider-Man animated universe!

Ardal O'Hanlon

as Electro in Casting a Spider-Man animated universe!

Zeno Robinson

as Harry Osborn in Casting a Spider-Man animated universe!

Marisa Tomei

as Aunt May in Casting a Spider-Man animated universe!

Mark Rolston

as Norman Osborn in Marvel’s Spider-Man (reboot of MCU Universe)

Michael Shannon

as Norman Osborn in Marvel’s Spider-Man (reboot of MCU Universe)

Billy Crudup

as Norman Osborn in Spider Man: Alternate Universe

Josh Keaton

as Harry Osborn in Spider Man: Alternate Universe

Kate Hudson

as Mj in Spider Man: Alternate Universe

Xolo Maridueña

as Harry Osborn in Spider-Man (Cobra Kai cast edition)

J.K. Simmons

as J. Jonah Jameson in Spider-Man (Cobra Kai cast edition)

Martin Kove

as Adrian Toombs in Spider-Man (Cobra Kai cast edition)