Suggestions by @speedrail78

Rita Moreno

as Teresa Martinez in Open Heart

Amber Ruffin

as Shonda Turner in Open Heart

Jessica Leccia

as Dr. Lozoya in Open Heart

Laurence Fishburne

as Mike Knoblauch in Open Heart

James Corden

as Farley in Open Heart

Emily Skinner

as Annie in Open Heart

Tyra Banks

as Harper Emery in Open Heart

Bianca Lawson

as Sarah in Open Heart

Jessica Alba

as Ines Delarosa in Open Heart

Dúaa Karim

as Phoebe in Open Heart

Jabari Banks

as Elijah Greene in Open Heart

Tristin Mays

as Dolores Hudson in Open Heart

Justin Bartha

as Declan Nash in Open Heart

Sreenivasan

as Naveen Banerji in Open Heart

Anthony Keyvan

as Danny Cardinal in Open Heart

Bellamy Young

as Marlene in Open Heart

Dhafer L'Abidine

as Zaid Mirani in Open Heart

Michael Provost

as Landry Olsen in Open Heart

Zoë Kravitz

as Kyra Santana in Open Heart

Quincy Brown

as Rafael Aveiro in Open Heart