Suggestions by @skytalk

Joaquin Phoenix

as Lee in Bones and All (2002)

Regina King

as Maren Yearly in Bones and All (2002)

Willem Dafoe

as Brad in Bones and All (2002)

Ellen Barkin

as Janelle Kerns in Bones and All (2002)

Albert Brooks

as Jake in Bones and All (2002)

Isaach de Bankolé

as Frank Yearly in Bones and All (2002)

Udo Kier

as John Dumé in Queer (1994)

Victor Argo

as Dr. Hernandez in Queer (1994)

Benicio del Toro

as Chimu Bar guy in Queer (1994)

Vincent Gallo

as Winston Moor in Queer (1994)

Angela Lansbury

as Dr. Cotter in Queer (1994)

Randy Quaid

as Jim Cochran in Queer (1994)

Wim Wenders

as Mr. Cotter in Queer (1994)

Vangelis

as Composer in Queer (1994)

Tinto Brass

as Doctor in Queer (1994)

Sigourney Weaver

as Mary in Queer (1994)

Sam Neill

as John Dumé in Queer (1994)

Abel Ferrara

as Tom Weston in Queer (1994)

William Hurt

as Joe Guidry in Queer (1994)

David Thewlis

as Eugene Allerton in Queer (1994)