Suggestions by @skytalk

Howard Shore

as Composer in Bugonia (1995)

David Cronenberg

as Director in Bugonia (1995)

Robert Pattinson

as Inspector Dave Toschi in Zodiac (2027)

Bart Layton

as Director in Zodiac (2027)

Grace Zabriskie

as Jillian at Clone Party in Good Luck, Have Fun, Don't Die (1996)

Giancarlo Esposito

as Robert at Clone Party in Good Luck, Have Fun, Don't Die (1996)

Sara Paxton

as 8-year-old Ingrid in Good Luck, Have Fun, Don't Die (1996)

Sinbad

as Scott in Good Luck, Have Fun, Don't Die (1996)

Drake Bell

as The AI Boy in Good Luck, Have Fun, Don't Die (1996)

Janus Blythe

as Francis in Keeper (1975)

Freda Foh Shen

as Leslie in Keeper (1975)

Olympia Dukakis

as Louise in Keeper (1975)

Piper Laurie

as Julia in Keeper (1975)

Teri Garr

as Baghead 2 / Maggie in Keeper (1975)

Jennifer Salt

as Baghead 1 in Keeper (1975)

Nancy Allen

as Minka in Keeper (1975)

Johnny Whitaker

as Teenage Darren in Keeper (1975)

Robert Duvall

as Darren Westbridge in Keeper (1975)

Emilio Estevez

as Teenage Malcolm in Keeper (1975)

James Coburn

as Dr. Malcolm Westbridge in Keeper (1975)