Suggestions by @silvermoth

Roronoa Zoro (One Piece)

as One Piece in Franchises Greatest Characters

Jinbe (One Piece)

as One Piece in Franchises Greatest Characters

Sally Field

as Reverend Mother Cetea in Mera

Juno Temple

as Siren in Mera

Cassandra Nova

as Best Marvel Villain in Best And Worst Of Villains

GLaDOS

as Best Video Game Villain in Best And Worst Of Villains

Sadie Sink

as Sara in Jean Grey

John Goodman

as John Grey in Jean Grey

Marcia Cross

as Elaine Grey in Jean Grey

Lucy Liu

as Lilandra in Jean Grey

Jensen Ackles

as Cyclops in Jean Grey

Karl Urban

as Batman in Superman: Legacy

Ron Funches

as Tiger in An American Tail (Illumination reboot)

Weapon X

as Side Villains in Insomniac’s Wolverine

Lior Raz

as Eric Lenchner in Insomniac’s Wolverine

Hugh Laurie

as Lionel Luthor in Luthor

John Logan

as Writer in Luthor

Bill Skarsgård

as Alexander “Lex” Luthor in Luthor

Rachel Brosnahan

as Lois Lane in Luthor

Mark Mylod

as Director in Luthor