Suggestions by @rowenjackson

Awkwafina

as Penelope Pussycat in Space Jam (Live-Action Remake)

Diego Luna

as Speedy Gonzales in Space Jam (Live-Action Remake)

Vincent Cassel

as Pepé Le Pew in Space Jam (Live-Action Remake)

Jim Cummings

as Tazmanian Devil in Space Jam (Live-Action Remake)

Peter Dinklage

as Yosemite Sam in Space Jam (Live-Action Remake)

Paul Giamatti

as Elmer Fudd in Space Jam (Live-Action Remake)

Julie Andrews

as Granny in Space Jam (Live-Action Remake)

Paul Julian

as Road Runner in Space Jam (Live-Action Remake)

Benedict Cumberbatch

as Wile E. Coyote in Space Jam (Live-Action Remake)

Bill Murray

as Bill the Opossum in Space Jam (Live-Action Remake)

Wayne Knight

as Stan the Opossum in Space Jam (Live-Action Remake)

LeBron James

as Mike the Weasel in Space Jam (Live-Action Remake)

Eric Bauza

as Tweety in Space Jam (Live-Action Remake)

Bob Bergen

as Porky Pig in Space Jam (Live-Action Remake)

Jeff Bergman

as Sylvester in Space Jam (Live-Action Remake)

Eric Bauza

as Daffy Duck in Space Jam (Live-Action Remake)

Zendaya

as Lola Bunny in Space Jam (Live-Action Remake)

Tom Holland

as Bugs Bunny in Space Jam (Live-Action Remake)

Dwayne Johnson

as Dwayne "The Rock" Johnson in Space Jam A New Legacy (SuperSuck64 Version)

Charles Martinet

as Super Mario in Space Jam A New Legacy (SuperSuck64 Version)