Suggestions by @randyruiz

Willem Dafoe

as Gerald Osborn in Spider-Randy & Friends The Movie

Mila Kunis

as Chelsea Meador in Spider-Randy & Friends The Movie

Leonardo DiCaprio

as Jose Ruiz in Spider-Randy & Friends The Movie

James Franco

as Marty Osborn in Spider-Randy & Friends The Movie

Kristen Dunst

as Alexa Meador in Spider-Randy & Friends The Movie

Tobey Maguire

as Randy Ruiz in Spider-Randy & Friends The Movie