Suggestions by @rachel_nightwing

Dacre Montgomery

as Eugene "Flash" Thompson in Ultimate Spider-Man (2020)

Matthew McConaughey

as Norman Osborn in Ultimate Spider-Man (2020)

Emma Thompson

as May Parker in Ultimate Spider-Man (2020)

Sam Raimi

as Director in Ultimate Spider-Man (2020)

Wyatt Oleff

as Peter Parker in Ultimate Spider-Man (2020)

Danny DeVito

as Mole Man in Ultimate Fantastic Four (2004)

Jake Gyllenhaal

as Reed Richards in Ultimate Fantastic Four (2004)

Robert Downey Jr.

as Richard Parker in Ultimate Spider-Man: Venom (2003)

Joaquin Phoenix

as Eddie Brock Jr. in Ultimate Spider-Man: Venom (2003)

Bob Odenkirk

as Dr. Kurt Konnors in Ultimate Spider-Man: Venom (2003)

Christopher Eccleston

as Eddie Brock Sr. in Ultimate Spider-Man: Venom (2003)

Jensen Ackles

as Eugene «Flash» Thompson in Ultimate Spider-Man: Venom (2003)

Emma Thompson

as May Parker in Ultimate Spider-Man: Venom (2003)

Natalie Portman

as Mary Jane Watson in Ultimate Spider-Man: Venom (2003)

Anne Hathaway

as Gwen Stacy in Ultimate Spider-Man: Venom (2003)

Tobey Maguire

as Peter Parker in Ultimate Spider-Man: Venom (2003)

Brad Pitt

as Thor in The Ultimates (2002)

David Duchovny

as Hank Pym in The Ultimates (2002)

Edward Norton

as Bruce Banner in The Ultimates (2002)

Ralph Fiennes

as Charles Xavier in Ultimate X-Men (2001)