Suggestions by @mr_blue_sky
10,492 suggestions
Dennis Farina
as J. Jonah Jameson in Spider Man (1985)
Mary Stuart Masterson
as Liz Allan in Spider Man (1985)
Hugh Grant
as Dr. Herbert G. Moreau in His Creatures
David Dastmalchian
as Montgomery Kenton in His Creatures
James Woods
as Electro in Spider Man (1985)
Bob Hoskins
as Otto Octavius in Spider Man (1985)
Tim Curry
as Mysterio in Spider Man (1985)
Kyle Mooney
as Dr. Flug Slys in Villainous (Live Action)
Nicolas Cage
as "The Leader" in League Of Super Evil
David Tennant
as Mayor Norman Osborn in Casting a Spider-Man animated universe!
Roddy McDowall
as Professor Spencer Smythe in 80's Spider-Man Movie Series
Gloria Stuart
as May Parker in 80's Spider-Man Movie Series
Katherine Hepburn
as May Parker in 80's Spider-Man Movie Series
Jamey Sheridan
as Montana in 80's Spider-Man Movie Series
Dennis Farina
as J. Jonah Jameson in 80's Spider-Man Movie Series
Angus Scrimm
as Vulture in 80's Spider-Man Movie Series
Tim Curry
as Mysterio in 80's Spider-Man Movie Series
The Thing (Ben Grimm)
as Brian Hull in Which Characters should these YouTubers be?
Deadpool (Wade Wilson)
as Jim Caddick in Which Characters should these YouTubers be?
Jim Caddick
as Wade Wilson in Actors who can play Deadpool