Suggestions by @milesyeargain

Bruce Campbell

as Dr. Strange in Marvel Origins: The Defenders (2008)

Jamie Chung

as Colleen Wing in Marvel Origins: The Defenders (2008)

Charlie Hunnam

as Iron Fist in Marvel Origins: The Defenders (2008)

Hilary Swank

as Jessica Jones in Marvel Origins: The Defenders (2008)

Terry Crews

as Luke Cage in Marvel Origins: The Defenders (2008)

Kate Beckinsale

as Elektra in Marvel Origins: The Defenders (2008)

Matt Damon

as Daredevil in Marvel Origins: The Defenders (2008)

George Clooney

as Director Nicholas Joseph “Nick” Fury in Marvel Origins: Fantastic 4 (2007)

Stan Lee

as Cameo in Marvel Origins: Fantastic 4 (2007)

Danny DeVito

as Mole Man in Marvel Origins: Fantastic 4 (2007)

Adam Sandler

as Mole Man in Marvel Origins: Fantastic 4 (2007)

Adam Scott

as Dr. Doom in Marvel Origins: Fantastic 4 (2007)

FAKE

as The Thing in Marvel Origins: Fantastic 4 (2007)

Zac Efron

as Human Torch in Marvel Origins: Fantastic 4 (2007)

Natalie Portman

as Invisible Woman in Marvel Origins: Fantastic 4 (2007)

Josh Duhamel

as Mr. Fantastic in Marvel Origins: Fantastic 4 (2007)

Mariska Hargitay

as Deputy Director Valentina “Val” Allegra de Fontaine in Marvel Origins: Jessica Jones (2007)

George Clooney

as Director Nicholas Joseph “Nick” Fury in Marvel Origins: Jessica Jones (2007)

Stan Lee

as Cameo in Marvel Origins: Jessica Jones (2007)

Terry Crews

as Luke Cage in Marvel Origins: Jessica Jones (2007)