Suggestions by @mikeprater
710 suggestions
Mary Stuart Masterson
as Betty Brandt in Spider-Man: Most Wanted
Jessica Tandy
as Aunt May Parker in Spider-Man: Most Wanted
C. Thomas Howell
as Harry Osborn in Spider-Man: Most Wanted
Peter Cushing
as Adrian Toomes in Spider-Man: Most Wanted
John Rhys-Davies
as Sergei Kravinoff in Spider-Man: Most Wanted
Michael Biehn
as William Baker in Spider-Man: Most Wanted
John Lithgow
as Norman Osborn in Spider-Man: Most Wanted
Christopher McDonald
as Flash Thompson in Spider-Man: Most Wanted
Bob Hoskins
as Otto Octavius in Spider-Man: Most Wanted
Susan Ursitti
as Mary Jane "MJ" Watson in Spider-Man: Most Wanted
Brad Dourif
as Dmitri Smerdyakov in Spider-Man: Most Wanted
Jack Nicholson
as James Howlett in Spider-Man: Most Wanted
Christopher Lee
as Erik Lehnsherr in X-Men: Days of Future Past
Charles Dance
as Erk Lehnsherr (1960s) in X-Men: Age of Apocalypse
Christopher Lee
as Erik Lehnsherr (1980s) in X-Men: Age of Apocalypse
Christopher Lee
as Erik Lehnsherr in The Uncanny X-Men
Mark Hamill
as Johnny Storm in Spider-Man: Most Wanted
Stan Lee
as J. Jonah Jameson in Spider-Man: Most Wanted
Michael J. Fox
as Peter Parker in Spider-Man: Most Wanted
Gary Valentine
as Mr. Meaner in Captain Underpants