Suggestions by @mike1seravello

Butch Cassady & the Sundance Kid

as Dustin Hoffman in Roles That Actors / Actresses Were ALMOST Casted

Supergirl (1984)

as Dudley Moore in Roles That Actors / Actresses Were ALMOST Casted

Splash

as Dudley Moore in Roles That Actors / Actresses Were ALMOST Casted

Azteca (ANTZ)

as Drew Barrymore in Roles That Actors / Actresses Were ALMOST Casted

Knocked up

as Drew Barrymore in Roles That Actors / Actresses Were ALMOST Casted

Mary Jane Watson (Spider-Man Films)

as Drew Barrymore in Roles That Actors / Actresses Were ALMOST Casted

Vivian Ward

as Drew Barrymore in Roles That Actors / Actresses Were ALMOST Casted

Showgirls (1995)

as Drew Barrymore in Roles That Actors / Actresses Were ALMOST Casted

My Best Friend's Wedding

as Drew Barrymore in Roles That Actors / Actresses Were ALMOST Casted

Aileen Wuornos

as Drew Barrymore in Roles That Actors / Actresses Were ALMOST Casted

Dangerous Liaisons

as Drew Barrymore in Roles That Actors / Actresses Were ALMOST Casted

The Crucible (1996 film)

as Drew Barrymore in Roles That Actors / Actresses Were ALMOST Casted

Click

as Drew Barrymore in Roles That Actors / Actresses Were ALMOST Casted

Roxie Hart

as Drew Barrymore in Roles That Actors / Actresses Were ALMOST Casted

Chasing Amy

as Drew Barrymore in Roles That Actors / Actresses Were ALMOST Casted

Celebrity (1998)

as Drew Barrymore in Roles That Actors / Actresses Were ALMOST Casted

Sandra Dee

as Drew Barrymore in Roles That Actors / Actresses Were ALMOST Casted

Carol Anne Freeling

as Drew Barrymore in Roles That Actors / Actresses Were ALMOST Casted

Joker (BurtonVerse)

as Donald Sutherland in Roles That Actors / Actresses Were ALMOST Casted

The Family Stone

as Donald Sutherland in Roles That Actors / Actresses Were ALMOST Casted