Suggestions by @matthewsimmons

James Franco

as John Jameson in Chris Columbus' Spider-Man 2 (2004)

Susan Sarandon

as Rosie Octavius in Chris Columbus' Spider-Man 2 (2004)

Sam Neill

as Dr. Conners in Chris Columbus' Spider-Man 2 (2004)

Pierce Brosnan

as Otto Octavius in Chris Columbus' Spider-Man 2 (2004)

Freddie Prinze Jr.

as Harry Osborn in Chris Columbus' Spider-Man 2 (2004)

Jena Malone

as Mary Jane Watson in Chris Columbus' Spider-Man 2 (2004)

Jake Gyllenhaal

as Peter Parker in Chris Columbus' Spider-Man 2 (2004)

Sally Field

as Aunt May in Chris Columbus' Spider-Man 2 (2004)

Chris Columbus

as Director in Chris Columbus' Spider-Man 2 (2004)

R. Lee Ermey

as J. Jonah Jameson in Chris Columbus' Spider-Man 2 (2004)

Rosario Dawson

as Betty Brant in Chris Columbus' Spider-Man 2 (2004)

R. Lee Ermey

as J. Jonah Jameson in Chris Columbus' Spider-Man (2002)

Jason Isaacs

as Norman Osborn in Chris Columbus' Spider-Man (2002)

David Koepp

as Writer in Chris Columbus' Spider-Man (2002)

Ryan Phillippe

as Flash Thompson in Chris Columbus' Spider-Man (2002)

Rosario Dawson

as Betty Brant in Chris Columbus' Spider-Man (2002)

Freddie Prinze Jr.

as Harry Osborn in Chris Columbus' Spider-Man (2002)

Jena Malone

as Mary Jane Watson in Chris Columbus' Spider-Man (2002)

Jake Gyllenhaal

as Peter Parker in Chris Columbus' Spider-Man (2002)

Robin Williams

as Uncle Ben in Chris Columbus' Spider-Man (2002)