Suggestions by @kingbig

Laurie Metcalf

as Miss Lemon in Third Street

George Wendt

as Mayor Fitzhugh in Third Street

Kal Penn

as Mr. Yamashiro in Third Street

Tyrel Jackson Williams

as Chad LaSalle in Third Street

Ed Oxenbould

as Erwin Lawson in Third Street

Ty Simpkins

as Francis the Hustler in Third Street

Tyler Mane

as Mr. Grundler in Third Street

Erika Eleniak

as Mrs. Grundler in Third Street

Noah Jupe

as Captain Sticky in Third Street

Melissa Joan Hart

as Mrs. Griswald in Third Street

Ethan Suplee

as Mr. Blumberg in Third Street

Dulé Hill

as Mr. LaSalle in Third Street

Vanessa Williams

as Mrs. LaSalle in Third Street

Federico Castelluccio

as Bob Spinelli in Third Street

Katie Holmes

as Flo Spinelli in Third Street

Christopher Walken

as Dr. Rosenthal in Third Street

Hugo Weaving

as Dr. Phillium Benedict in Third Street

Kathy Bates

as Muriel P. Finster in Third Street

Tracey Gold

as Mrs. Blumberg in Third Street

Jim Parsons

as Professor Fenwick in Third Street