Suggestions by @khabib

Marisa Tomei

as Aunt May in Spider-Man 4 (2026)

Sandrine Holt

as Vanessa Fisk in Spider-Man 4 (2026)

Angourie Rice

as Betty Brant in Spider-Man 4 (2026)

Tony Revolori

as Flash Thompson in Spider-Man 4 (2026)

Wendell Pierce

as Joseph "Robbie" Robertson in Spider-Man 4 (2026)

Jacob Batalon

as Ned Leeds in Spider-Man 4 (2026)

J.K. Simmons

as J. Jonah Jameson in Spider-Man 4 (2026)

Zendaya

as Michelle Jones in Spider-Man 4 (2026)

Wes Bentley

as Hammerhead in Spider-Man 4 (2026)

Lucas Till

as Iron Fist in Spider-Man 4 (2026)

Mehcad Brooks

as Luke Cage in Spider-Man 4 (2026)

Mary Elizabeth Winstead

as Jessica Jones in Spider-Man 4 (2026)

Wilson Bethel

as Bullseye in Spider-Man 4 (2026)

Alaqua Cox

as Echo in Spider-Man 4 (2026)

Donald Glover

as Prowler in Spider-Man 4 (2026)

Michael Mando

as Scorpion in Spider-Man 4 (2026)

Hailee Steinfeld

as Lady Hawkeye in Spider-Man 4 (2026)

Elle Fanning

as Gwen Stacy in Spider-Man 4 (2026)

Charlie Cox

as Daredevil in Spider-Man 4 (2026)

Vincent D'Onofrio

as Kingpin in Spider-Man 4 (2026)