Suggestions by @bumbleprime

Bill Hader

as Quentin Beck in Spider-Man live action Series

Liam Neeson

as Dr. Otto Octavius in Spider-Man live action Series

Joaquin Phoenix

as Dr. Norman Osborn in Spider-Man live action Series

Amy Adams

as May Parker in Spider-Man live action Series

Sophia Lillis

as Gwen Stacy in Spider-Man live action Series

Isabela Merced

as Mary Jane Watson in Spider-Man live action Series

Asher Angel

as Peter Parker in Spider-Man live action Series

Peter Griffin

as Kevin James in What characters would these actors play in live action?

Elita-1 (Transformers)

as Reese Witherspoon in What characters would these actors play in live action?

Ellie (Ice Age)

as Reese Witherspoon in What characters would these actors play in live action?

Manny (Ice Age)

as Dwayne Johnson in What characters would these actors play in live action?

Jazz (Transformers)

as Kevin Hart in What characters would these actors play in live action?

Sigourney Weaver

as The Narrator in Cartoon World: The Series (A Father & Son)

Kevin Michael Richardson

as Big Muscled Henchman in Cartoon World: The Series (A Father & Son)

Jim Cummings

as Big Fat Henchman in Cartoon World: The Series (A Father & Son)

Dee Bradley Baker

as Short Henchman in Cartoon World: The Series (A Father & Son)

Alec Baldwin

as Spike The Bulldog in Cartoon World: The Series (A Father & Son)

Alan Tudyk

as Jerry Mouse in Cartoon World: The Series (A Father & Son)

Seth MacFarlane

as Tom Cat in Cartoon World: The Series (A Father & Son)

Jeff Bergman

as Daffy Duck in Cartoon World: The Series (A Father & Son)