Suggestions by @bennystrikesback

Willem Dafoe

as Mephisto in Spider-Man

Jenna Ortega

as Anya Corazón in Spider-Man

Sophia Lillis

as Martha “Mattie” Franklin in Spider-Man

Maya Hawke

as Spider-Girl in Spider-Man

Kathryn Hunter

as Madame Web in Spider-Man

Rosie Huntington-Whiteley

as Julia Carpenter in Spider-Man

Ella Purnell

as Spider-Woman in Spider-Man

Tao Okamoto

as Yuriko Watanabe in Spider-Man

Robert De Niro

as Leo Zelinski in Spider-Man

Saffron Burrows

as Dr. Ashley Kafka in Spider-Man

Sylvia Hoeks

as Silver Sable in Spider-Man

Summer Glau

as Jean DeWolff in Spider-Man

Alan Ritchson

as The Punisher in Spider-Man

Billy Crudup

as Police Captain George Stacy in Spider-Man

Elodie Grace Orkin

as Elizabeth “Liz” Allan in Spider-Man

Aaron Pierre

as Spider-Punk in Spider-Man

Miyako

as Peni Parker in Spider-Man

Joaquin Phoenix

as Spider-Man Noir in Spider-Man

Rohan Chand

as Spider-Man India in Spider-Man

Gael García Bernal

as Spider-Man 2099 in Spider-Man