Suggestions by @aleksimalkavaara

Joseph Wiseman

as Best (Mad) Scientist in Best & Worst of Sci-Fi

Jeff Goldblum

as Best (Mad) Scientist in Best & Worst of Sci-Fi

Justin Roiland

as Best (Mad) Scientist in Best & Worst of Sci-Fi

David Herman

as Best (Mad) Scientist in Best & Worst of Sci-Fi

Billy West

as Best (Mad) Scientist in Best & Worst of Sci-Fi

Junpei Takiguchi

as Best (Mad) Scientist in Best & Worst of Sci-Fi

Brent Spiner

as Best (Mad) Scientist in Best & Worst of Sci-Fi

Joe Seneca

as Best (Mad) Scientist in Best & Worst of Sci-Fi

Wilford Brimley

as Best (Mad) Scientist in Best & Worst of Sci-Fi

Tilo Prückner

as Best (Mad) Scientist in Best & Worst of Sci-Fi

James Hong

as Best (Mad) Scientist in Best & Worst of Sci-Fi

Joe Turkel

as Best (Mad) Scientist in Best & Worst of Sci-Fi

Hideyo Amamoto

as Best (Mad) Scientist in Best & Worst of Sci-Fi

Akihiko Hirata

as Best (Mad) Scientist in Best & Worst of Sci-Fi

Rudolf Klein-Rogge

as Best (Mad) Scientist in Best & Worst of Sci-Fi

Christopher Lloyd

as Best (Mad) Scientist in Best & Worst of Sci-Fi

Christopher Lloyd

as Best Actor in Best & Worst of Sci-Fi

Alan Silvestri

as Best Composer in Best & Worst of Sci-Fi

Jessica Alba

as Worst Actress in Best & Worst of Sci-Fi

Tim Story

as Worst Director in Best & Worst of Sci-Fi