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A high-class prostitute by choice, Nelly Arcan’s colorful life is recreated in a multi-layered and stylish mix of make-believe and memoir, revealing Nelly’s alter egos: the neurotic writer, the vulnerable lover, the call girl and the star. Nelly shocked the literary world with her elegant writing and the lurid details of sex work in her autobiographical first novel, Whore, which became a critically acclaimed bestseller. Despite unprecedented success, Nelly’s remarkable life ended in tragedy.
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The Gamache, tailors from father to son, have been dressing the Mafia family Paternò for three generation. Vincent "Vince" Gamache works on behalf of Frank the godfather with his eldest son Giaco. Vince, reckless and rash, seeks to earn his stripes by impressing the godfather. Without the Paternò knowing, he stages a big operation and is promoted. Fuming with jealousy, Giaco discovers that Vince committed a monstrous act during his stroke. The Gamache disown Vince and war begins.
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Twelve-year-old Simone feels painfully disconnected from the world after witnessing the brutal death of her mother. Simone, a solitary multimedia artist in her twenties, is struggling to control her crushing panic attacks and keep her day job in an underground parking lot. And Simone, a sixty-year-old physicist, is giving a conference on the nature of time. The three Simones' lives are intertwined in a labyrinthine meta-world where timeframes overlap, characters multiply, and storylines repeat and expand. But, for all its shuttling forward and back through time, ENDORPHINE remains grounded in the Simones' inner lives — it's an artistic examination of scientific phenomena that also poignantly explores how people deal with trauma.