After years of being mostly abandoned, the CN City is reborn as if it never left. But not all bodes well, as ACME president Bruno Mannheim searches for the Anti-Life Equation and decides that it could be in CN City, so he sends hired assassins The Kanker Sisters, Wile E Coyote, Mrs Robinson, Toiletnator, and Vilgax in attempt to retrieve it. Dexter gets note of this and tries to round up new toon Wendell Wombat, as he senses that this may be who they are looking for. Along the way, the two also meet up with Bugs Bunny, Daffy Duck, Samurai Jack, Johnny Bravo, Mystery Incorporated, The Ed’s, The Powerpuff Girls, Ami and Yumi, Gumball and Darwin, Courage, Ben 10, Grim Billy and Mandy, Sector V And Finn and Jake.
