Leon S. Kennedy and his partner, Helena Harper, deal with a viral outbreak in the U.S. after the President is infected. Chris and his team battle the bioterrorist organization Neo-Umbrella, led by the mysterious Carla Radames. Jake, the son of series antagonist Albert Wesker, teams up with Sherry Birkin to escape Neo-Umbrella's clutches, as his blood holds the key to a vaccine. Ada, working alone, uncovers the truth behind the global conspiracy orchestrated by Carla. The story culminates in the protagonists joining forces to stop the spread of the C-Virus and bring the culprits to justice.
