Set in a near-future waterfront city like Chicago or Seattle - in a conformist nanny/police-state, Faith Connors is an illegal courier or "runner", whose job it is to hand-deliver messages and data across the rooftops and skyways to avoid ubiquitous government monitoring of movement and communications. After making a few deliveries, private security firm Pirandello Kruger and Silvine contracts a secret mole to kill a family friend.
The story follows Faith in her struggle to free her unjustly-imprisoned sister, accused of murdering a friend of their family - Mayoral Candidate Robert Pope. While running clients' illegal messages, she gets caught up in events which lead to her being endlessly pursued by the totalitarian government herself. Mercury, Faith's trainer/mentor, acts as her guide to outwit, outrun, and overcome the sinister agents out to eliminate her.