Professor Philip Brainard is experimenting with new kinds of energy, and he thinks this project will save struggling Medfield College, where his girlfriend, Sara, is president. But when he discovers a lively, rubber-like substance dubbed "flubber," he gets so excited, he absent-mindedly misses his own wedding. Sara dumps him, so he tries to use his discovery to win her back; unfortunately, the mischievous flubber seems to have a mind of its own.