In Ben Tennyson's universe, people mysteriously began to disappear (Including Gwen, Kevin, Julie, Sandra, Carl, Ester & Rook & others), while in Rex Salazar's universe, the power of the people of the EVO group began to disappear. Ben & Rex receives a message from Max Tennyson and Agent Six, in which they learn that both worlds are in danger because of Vilgax, Van Kleiss & other villains, have completely united and invaded these worlds to destroy everything and build a new towers that will unite only evil and the undead. Ben and Rex must team up again to save the world from the invasion of Vilgax, Van Kleiss & other villains, and save everyone.
